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The Histone Deacetylase Inhibitor Entinostat Enhances Polymer-Mediated Transgene Expression in Cancer Cell Lines

Eukaryotic cells maintain an immense amount of genetic information by tightly wrapping their DNA around positively charged histones. While this strategy allows human cells to maintain more than 25,000 genes, histone binding can also block gene expression. Consequently, cells express histone acetyl t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Biotechnol Bioeng
Päätekijät: Elmer, Jacob J., Christensen, Matthew D., Barua, Sutapa, Lehrman, Jennifer, Haynes, Karmella A., Rege, Kaushal
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5140276/
https://ncbi.nlm.nih.gov/pubmed/26614912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.25898
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