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Combinatorial effects of histone deacetylase inhibitors (HDACi), vorinostat and entinostat, and adaphostin are characterized by distinct redox alterations
PURPOSE: Amongst the epigenetically-targeted therapies, targeting of the histone deacetylases (HDACs) has yielded numerous drugs for clinical use in hematological malignancies, but none as yet for acute lymphocytic leukemia (ALL). Single agent activity of HDAC inhibitors (HDACi) has been elusive in...
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| Publicado no: | Cancer Chemother Pharmacol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5837827/ https://ncbi.nlm.nih.gov/pubmed/29313067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-017-3509-0 |
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