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Histone deacetylase inhibitors (HDACIs): multitargeted anticancer agents

Histone deacetylase (HDAC) inhibitors are an emerging class of therapeutics with potential as anticancer drugs. The rationale for developing HDAC inhibitors (and other chromatin-modifying agents) as anticancer therapies arose from the understanding that in addition to genetic mutations, epigenetic c...

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Detalhes bibliográficos
Main Authors: Ververis, Katherine, Hiong, Alison, Karagiannis, Tom C, Licciardi, Paul V
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584656/
https://ncbi.nlm.nih.gov/pubmed/23459471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BTT.S29965
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