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Reprogramming of TLR7 signaling enhances antitumor NK and cytotoxic T cell responses
Toll-like receptor (TLR) 7 agonists are effective in topical application for the immunotherapy of skin cancers, but their performance for the systemic treatment of solid tumors is limited by the development of TLR tolerance. In this study, we describe a novel strategy to overcome TLR tolerance and e...
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Publicado no: | Oncoimmunology |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Taylor & Francis
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5139637/ https://ncbi.nlm.nih.gov/pubmed/27999742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1232219 |
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