TLR7-based cancer immunotherapy decreases intratumoral myeloid-derived suppressor cells and blocks their immunosuppressive function

Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of immature myeloid cells with the capacity to inhibit immunological responses. During cancer progression, MDSC are recruited to the tumor sites and secondary lymphoid organs, leading to the suppression of the antitumor function...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Spinetti, Thibaud, Spagnuolo, Lorenzo, Mottas, Inès, Secondini, Chiara, Treinies, Marina, Rüegg, Curzio, Hotz, Christian, Bourquin, Carole
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5139641/
https://ncbi.nlm.nih.gov/pubmed/27999739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1230578
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