TLR7-based cancer immunotherapy decreases intratumoral myeloid-derived suppressor cells and blocks their immunosuppressive function

Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of immature myeloid cells with the capacity to inhibit immunological responses. During cancer progression, MDSC are recruited to the tumor sites and secondary lymphoid organs, leading to the suppression of the antitumor function...

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Bibliografski detalji
Izdano u:Oncoimmunology
Glavni autori: Spinetti, Thibaud, Spagnuolo, Lorenzo, Mottas, Inès, Secondini, Chiara, Treinies, Marina, Rüegg, Curzio, Hotz, Christian, Bourquin, Carole
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2016
Teme:
Original Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5139641/
https://ncbi.nlm.nih.gov/pubmed/27999739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1230578
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