Cytoreduction surgery reduces systemic myeloid suppressor cell populations and restores intratumoral immunotherapy effectiveness

BACKGROUND: Multiple immunotherapy approaches have improved adaptive anti-tumor immune responses in patients with early stage disease; however, results have been less dramatic when treating patients with late stage disease. These blunted responses are likely due to a host of factors, including chang...

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Autors principals: Predina, Jarrod D, Kapoor, Veena, Judy, Brendan F, Cheng, Guanjun, Fridlender, Zvi Gregory, Albelda, Steven M, Singhal, Sunil
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418164/
https://ncbi.nlm.nih.gov/pubmed/22742411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-5-34
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