A positive-margin resection model recreates the postsurgical tumor microenvironment and is a reliable model for adjuvant therapy evaluation

Up to 30% of cancer patients undergoing curative surgery develop local recurrences due to positive margins. Patients typically receive adjuvant chemotherapy, immunotherapy and/or radiation to prevent such relapses. Interestingly, evidence supporting these therapies is traditionally derived in animal...

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Detalhes bibliográficos
Main Authors: Predina, Jarrod D., Judy, Brendan, Fridlender, Zvi G., Aliperti, Louis A., Madajewski, Brian, Kapoor, Veena, Cheng, Guanjun, Quatromoni, Jon, Okusanya, Olugbenga, Singhal, Sunil
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606205/
https://ncbi.nlm.nih.gov/pubmed/22617772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.20557
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