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Systemic cancer immunotherapy with Toll-like receptor 7 agonists: Timing is everything

Toll-like receptor (TLR) 7 agonists represent a promising strategy for the immunotherapy of cancer. We have recently investigated the influence of TLR tolerance on the efficacy of systemic tumor treatment with TLR7 ligands. We propose that considering the kinetics of receptor sensitivity highly impr...

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Detalhes bibliográficos
Main Authors: Hotz, Christian, Bourquin, Carole
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376978/
https://ncbi.nlm.nih.gov/pubmed/22720251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.1.2.18169
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