Facile syntheses of functionalized toll-like receptor 7 agonists

Protein conjugates of toll-like receptor 7 agonists have been shown to elicit powerful immune responses. In order to facilitate our studies in this area our group has developed efficient syntheses for a number of functionalized derivatives that retain immune stimulatory activity.

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Detalhes bibliográficos
Publicado no:Tetrahedron Lett
Main Authors: Akinbobuyi, Babatope, Byrd, Matthew R., Chang, Charles A., Nguyen, Mysa, Seifert, Zacharie J., Flamar, Anne-Laure, Zurawski, Gerard, Upchurch, Katherine C., Oh, SangKon, Dempsey, Stephen H., Enke, Thomas J., Le, John, Winstead, Hunter J., Boquín, José R., Kane, Robert R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296738/
https://ncbi.nlm.nih.gov/pubmed/25601818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2014.11.126
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