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Dectin-1 Controls TSLP-Induced Th2 Response by Regulating STAT3, STAT6, and p50-RelB Activities in Dendritic Cells

The epithelium-associated cytokine thymic stromal lymphopoietin (TSLP) can induce OX40L and CCL17 expression by myeloid dendritic cells (mDCs), which contributes to aberrant Th2-type immune responses. Herein, we report that such TSLP-induced Th2-type immune response can be effectively controlled by...

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Publicado en:Front Immunol
Autores principales: Gu, Chao, Upchurch, Katherine, Horton, Joshua, Wiest, Mathew, Zurawski, Sandra, Millard, Mark, Kane, Robert R., Joo, HyeMee, Miller, Lisa A., Oh, SangKon
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8293820/
https://ncbi.nlm.nih.gov/pubmed/34305908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.678036
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