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p50–NF-κB Complexes Partially Compensate for the Absence of RelB: Severely Increased Pathology in p50(−) (/−) relB(−) (/−)Double-knockout Mice

RelB-deficient mice (relB(−) (/−)) have a complex phenotype including multiorgan inflammation and hematopoietic abnormalities. To examine whether other NF-κB/Rel family members are required for the development of this phenotype or have a compensatory role, we have initiated a program to generate dou...

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Hlavní autoři: Weih, Falk, Durham, Stephen K., Barton, Debra S., Sha, William C., Baltimore, David, Bravo, Rodrigo
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1997
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196264/
https://ncbi.nlm.nih.gov/pubmed/9104822
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