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RelB is required for Peyer’s patch development: differential regulation of p52–RelB by lymphotoxin and TNF

Targeted disruption of the Rel/NF-κB family members NF-κB2, encoding p100/p52, and RelB in mice results in anatomical defects of secondary lymphoid tissues. Here, we report that development of Peyer’s patch (PP)-organizing centers is impaired in both NF-κB2- and RelB-deficient animals. IL-7-induced...

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Autores principales: Yilmaz, Z.Buket, Weih, Debra S., Sivakumar, Vallabhapurapu, Weih, Falk
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC140043/
https://ncbi.nlm.nih.gov/pubmed/12505990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg004
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