Concomitant activation and antigen uptake via human Dectin-1 results in potent antigen-specific CD8(+) T cell responses

Dectin-1, a C-type lectin recognizing fungal and mycobacterial pathogens, can deliver intracellular signals that activate dendritic cells (DCs), resulting in initiation of immune responses and expansion of Th17 CD4(+) T cell responses. Here, we studied the roles of human Dectin-1 (hDectin-1) express...

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Autores principales: Ni, Ling, Gayet, Ingrid, Zurawski, Sandra, Duluc, Dorothee, Flamar, Anne-Laure, Li, Xiao-Hua, O’Bar, Amy, Clayton, Sandra, Palucka, Anna Karolina, Zurawski, Gerard, Banchereau, Jacques, Oh, SangKon
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941972/
https://ncbi.nlm.nih.gov/pubmed/20729328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000999
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