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Concomitant activation and antigen uptake via human Dectin-1 results in potent antigen-specific CD8(+) T cell responses
Dectin-1, a C-type lectin recognizing fungal and mycobacterial pathogens, can deliver intracellular signals that activate dendritic cells (DCs), resulting in initiation of immune responses and expansion of Th17 CD4(+) T cell responses. Here, we studied the roles of human Dectin-1 (hDectin-1) express...
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| Auteurs principaux: | , , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2941972/ https://ncbi.nlm.nih.gov/pubmed/20729328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000999 |
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