Arginase inhibition suppresses lung metastasis in the 4T1 breast cancer model independently of the immunomodulatory and anti-metastatic effects of VEGFR-2 blockade

Tumor angiogenesis promotes tumor growth and metastasis. Anti-angiogenic therapy in combination with chemotherapy is used for the treatment of metastatic cancers, including breast cancer but therapeutic benefits are limited. Mobilization and accumulation of myeloid-derived suppressor cells (MDSC) du...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Oncoimmunology
Huvudupphovsmän: Secondini, Chiara, Coquoz, Oriana, Spagnuolo, Lorenzo, Spinetti, Thibaud, Peyvandi, Sanam, Ciarloni, Laura, Botta, Francesca, Bourquin, Carole, Rüegg, Curzio
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2017
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486183/
https://ncbi.nlm.nih.gov/pubmed/28680747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1316437
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk