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Arginase Blockade Lessens Endothelial Dysfunction After Thrombosis

INTRODUCTION: Acute arterial thrombosis causes endothelial dysfunction due to decreased nitric oxide (NO) bioactivity. Increased arginase activity may modulate intracellular L-arginine levels, the substrate for NO. The purpose of this study was to identify the role of arginase in endothelial dysfunc...

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Main Authors: Lewis, Chandani, Zhu, Weifei, Pavkov, Mircea L., Kinney, Corttrell M., DiCorleto, Paul E., Kashyap, Vikram S.
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517129/
https://ncbi.nlm.nih.gov/pubmed/18486420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvs.2008.02.030
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