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Thrombin induces endothelial arginase through AP-1 activation

Arterial thrombosis is a common disease leading to severe ischemia beyond the obstructing thrombus. Additionally, endothelial dysfunction at the site of thrombosis can be rescued by l-arginine supplementation or arginase blockade in several animal models. Exposure of rat aortic endothelial cells (RA...

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Autori principali: Zhu, Weifei, Chandrasekharan, Unni M., Bandyopadhyay, Smarajit, Morris, Sidney M., DiCorleto, Paul E., Kashyap, Vikram S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853217/
https://ncbi.nlm.nih.gov/pubmed/20032511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00466.2009
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