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Development of Novel Arginase Inhibitors for Therapy of Endothelial Dysfunction

Endothelial dysfunction and resulting vascular pathology have been identified as an early hallmark of multiple diseases, including diabetes mellitus. One of the major contributors to endothelial dysfunction is a decrease in nitric oxide (NO) bioavailability, impaired NO signaling, and an increase in...

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Detalhes bibliográficos
Main Authors: Steppan, Jochen, Nyhan, Daniel, Berkowitz, Dan E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774993/
https://ncbi.nlm.nih.gov/pubmed/24062745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00278
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