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Development of Novel Arginase Inhibitors for Therapy of Endothelial Dysfunction

Endothelial dysfunction and resulting vascular pathology have been identified as an early hallmark of multiple diseases, including diabetes mellitus. One of the major contributors to endothelial dysfunction is a decrease in nitric oxide (NO) bioavailability, impaired NO signaling, and an increase in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Steppan, Jochen, Nyhan, Daniel, Berkowitz, Dan E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774993/
https://ncbi.nlm.nih.gov/pubmed/24062745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00278
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