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Increased arginase II activity contributes to endothelial dysfunction through endothelial nitric oxide synthase uncoupling in aged mice

The incidence of cardiovascular disease is predicted to increase as the population ages. There is accumulating evidence that arginase upregulation is associated with impaired endothelial function. Here, we demonstrate that arginase II (ArgII) is upregulated in aortic vessels of aged mice and contrib...

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書誌詳細
主要な著者: Shin, Woosung, Berkowitz, Dan E., Ryoo, Sungwoo
フォーマット: Artigo
言語:Inglês
出版事項: Korean Society for Biochemistry and Molecular Biology 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490081/
https://ncbi.nlm.nih.gov/pubmed/22854495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2012.44.10.068
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