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Increased arginase II activity contributes to endothelial dysfunction through endothelial nitric oxide synthase uncoupling in aged mice

The incidence of cardiovascular disease is predicted to increase as the population ages. There is accumulating evidence that arginase upregulation is associated with impaired endothelial function. Here, we demonstrate that arginase II (ArgII) is upregulated in aortic vessels of aged mice and contrib...

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Autori principali: Shin, Woosung, Berkowitz, Dan E., Ryoo, Sungwoo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Korean Society for Biochemistry and Molecular Biology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490081/
https://ncbi.nlm.nih.gov/pubmed/22854495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2012.44.10.068
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