Učitavanje...
Arginase Inhibition Reverses Endothelial Dysfunction, Pulmonary Hypertension and Vascular Stiffness in Transgenic Sickle Cell Mice
BACKGROUND: In sickle cell disease (SCD), hemolysis results in the release and activation of arginase, an enzyme that reciprocally regulates nitric oxide (NO) synthase activity and thus, NO production. However, simply supplementing the common substrate L-arginine fails to improve NO bioavailability....
Spremljeno u:
| Izdano u: | Anesth Analg |
|---|---|
| Glavni autori: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
|
| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5032625/ https://ncbi.nlm.nih.gov/pubmed/27537757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0000000000001378 |
| Oznake: |
Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!
|