Prevention of DNA damage in Barrett’s esophageal cells exposed to acidic bile salts

Esophageal adenocarcinoma (EA) is one of the fastest rising tumors in the USA. The major risk factor for EA is gastroesophageal reflux disease (GERD). During GERD, esophageal cells are exposed to refluxate which contains gastric acid frequently mixed with duodenal bile. This may lead to mucosal inju...

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Publicat a:Carcinogenesis
Autors principals: Bhardwaj, Vikas, Horvat, Andela, Korolkova, Olga, Washington, Mary K., El-Rifai, Wael, Dikalov, Sergey I., Zaika, Alexander I.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
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Original Manuscript
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137263/
https://ncbi.nlm.nih.gov/pubmed/27655834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgw100
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