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APE1-mediated DNA damage repair provides survival advantage for esophageal adenocarcinoma cells in response to acidic bile salts

Chronic Gastroesophageal Reflux Disease (GERD) is the main risk factor for the development of Barrett's esophagus (BE) and its progression to esophageal adenocarcinoma (EAC). Accordingly, EAC cells are subjected to high levels of oxidative stress and subsequent DNA damage. In this study, we inv...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Hong, Jun, Chen, Zheng, Peng, Dunfa, Zaika, Alexander, Revetta, Frank, Washington, M. Kay, Belkhiri, Abbes, El-Rifai, Wael
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941344/
https://ncbi.nlm.nih.gov/pubmed/26934647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7696
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