APE1-mediated DNA damage repair provides survival advantage for esophageal adenocarcinoma cells in response to acidic bile salts

Chronic Gastroesophageal Reflux Disease (GERD) is the main risk factor for the development of Barrett's esophagus (BE) and its progression to esophageal adenocarcinoma (EAC). Accordingly, EAC cells are subjected to high levels of oxidative stress and subsequent DNA damage. In this study, we inv...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Hong, Jun, Chen, Zheng, Peng, Dunfa, Zaika, Alexander, Revetta, Frank, Washington, M. Kay, Belkhiri, Abbes, El-Rifai, Wael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2016
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941344/
https://ncbi.nlm.nih.gov/pubmed/26934647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7696
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