The Aurora kinase A inhibitor MLN8237 Enhances Cisplatin-induced Cell Death in Esophageal Adenocarcinoma Cells

Esophageal adenocarcinomas (EACs) are poorly responsive to chemotherapeutics. This study aimed to determine the levels of Aurora kinas A (AURKA) and the therapeutic potential of MLN8237, an investigational AURKA inhibitor, alone and in combination with Cisplatin. Using quantitative real time polymer...

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Autors principals: Sehdev, Vikas, Peng, DunFa, Soutto, Mohammed, Washington, M. Kay, Revetta, Frank, Ecsedy, Jeffrey, Zaika, Alexander, Tilman, Rau, Schneider-Stock, Regine, Belkhiri, Abbes, El-Rifai, Wael
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297687/
https://ncbi.nlm.nih.gov/pubmed/22302096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-11-0623
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