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Glutathione peroxidase 7 has potential tumor suppressor functions that are silenced by location-specific methylation in oesophageal adenocarcinoma

OBJECTIVE: We investigated the potential tumor suppressor functions of glutathione peroxidase 7 (GPX7) and examined the interplay between epigenetic and genetic events in regulating its expression in oesophageal adenocarcinomas (OAC). DESIGN: In vitro and in vivo cell models were developed to invest...

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Detalhes bibliográficos
Main Authors: Peng, DunFa, Hu, TianLing, Soutto, Mohammed, Belkhiri, Abbes, Zaika, Alexander, El-Rifai, Wael
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825783/
https://ncbi.nlm.nih.gov/pubmed/23580780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2013-304612
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