DNA hypermethylation regulates the expression of members of the Mu-class Glutathione-S-Transferases and Glutathione Peroxidases in Barrett's adenocarcinoma

BACKGROUND: The accumulation of reactive oxygen species and subsequent oxidative DNA damage underlie the development of Barrett's esophagus (BE) and its progression to Barrett's dysplasia (BD) and adenocarcinoma (BAC). METHODS: We systematically analyzed the promoter regions of 23 genes of...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Peng, DunFa, Razvi, Mohammad, Chen, Heidi, Washington, Kay, Roessner, Albert, Schneider-Stock, Regine, El-Rifai, Wael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845391/
https://ncbi.nlm.nih.gov/pubmed/18664505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2007.146290
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