Hypermethylation and Loss of Expression of Glutathione Peroxidase-3 in Barrett's Tumorigenesis

Chronic gastroesophageal reflux disease is a known risk factor for Barrett's esophagus (BE), that induces oxidative mucosal damage. Glutathione peroxidase-3 (GPx3) is a secretory protein with potent extracellular antioxidant activity. Herein, we have investigated the mRNA and protein expression...

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Autori principali: Lee, Ok-Jae, Schneider-Stock, Regine, McChesney, Patricia A, Kuester, Doerthe, Roessner, Albert, Vieth, Michael, Moskaluk, Christopher A, El-Rifai, Wa'el
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press Inc. 2005
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1501938/
https://ncbi.nlm.nih.gov/pubmed/16229808
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