Promoter Hypermethylation and Suppression of Glutathione Peroxidase 3 Are Associated with Inflammatory Breast Carcinogenesis

Reactive oxygen species (ROS) play a crucial role in breast cancer initiation, promotion, and progression. Inhibition of antioxidant enzymes that remove ROS was found to accelerate cancer growth. Studies showed that inhibition of glutathione peroxidase-3 (GPX3) was associated with cancer progression...

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Hlavní autoři: Mohamed, Mona M., Sabet, Salwa, Peng, Dun-Fa, Nouh, M. Akram, El-Shinawi, Mohamed, El-Rifai, Wael
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980917/
https://ncbi.nlm.nih.gov/pubmed/24790704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/787195
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