Silencing of Glutathione Peroxidase 3 through DNA Hypermethylation Is Associated with Lymph Node Metastasis in Gastric Carcinomas

Gastric cancer remains the second leading cause of cancer-related death in the world. H. pylori infection, a major risk factor for gastric cancer, generates high levels of reactive oxygen species (ROS). Glutathione peroxidase 3 (GPX3), a plasma GPX member and a major scavenger of ROS, catalyzes the...

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Main Authors: Peng, Dun-Fa, Hu, Tian-Ling, Schneider, Barbara G., Chen, Zheng, Xu, Ze-Kuan, El-Rifai, Wael
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468580/
https://ncbi.nlm.nih.gov/pubmed/23071548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046214
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