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NRF2 antioxidant response protects against acidic bile salts-induced oxidative stress and DNA damage in esophageal cells
Gastroesophageal reflux disease (GERD) is the main risk factor for Barrett’s tumorigenesis. In this study, we investigated the role of NRF2 in response to exposure acidic bile salts (ABS), in conditions that mimic GERD, using Barrett’s esophagus cell models. We detected an increase in NRF2 protein l...
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| Опубликовано в: : | Cancer Lett |
|---|---|
| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6571054/ https://ncbi.nlm.nih.gov/pubmed/31132430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2019.05.031 |
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