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NRF2 antioxidant response protects against acidic bile salts-induced oxidative stress and DNA damage in esophageal cells

Gastroesophageal reflux disease (GERD) is the main risk factor for Barrett’s tumorigenesis. In this study, we investigated the role of NRF2 in response to exposure acidic bile salts (ABS), in conditions that mimic GERD, using Barrett’s esophagus cell models. We detected an increase in NRF2 protein l...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Lett
Egile Nagusiak: Peng, Dunfa, Lu, Heng, Zhu, Shoumin, Zhou, Zhangjian, Hu, Tianling, Chen, Zheng, Zaika, Alexander, El-Rifai, Wael
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6571054/
https://ncbi.nlm.nih.gov/pubmed/31132430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2019.05.031
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