Prevention of DNA damage in Barrett’s esophageal cells exposed to acidic bile salts

Esophageal adenocarcinoma (EA) is one of the fastest rising tumors in the USA. The major risk factor for EA is gastroesophageal reflux disease (GERD). During GERD, esophageal cells are exposed to refluxate which contains gastric acid frequently mixed with duodenal bile. This may lead to mucosal inju...

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Bibliografiska uppgifter
I publikationen:Carcinogenesis
Huvudupphovsmän: Bhardwaj, Vikas, Horvat, Andela, Korolkova, Olga, Washington, Mary K., El-Rifai, Wael, Dikalov, Sergey I., Zaika, Alexander I.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2016
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Original Manuscript
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137263/
https://ncbi.nlm.nih.gov/pubmed/27655834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgw100
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