Activation of NADPH oxidases leads to DNA damage in esophageal cells

Gastroesophageal reflux disease (GERD) is the strongest known risk factor for esophageal adenocarcinoma. In the center of tumorigenic events caused by GERD is repeated damage of esophageal tissues by the refluxate. In this study, we focused on a genotoxic aspect of exposure of esophageal cells to ac...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bhardwaj, Vikas, Gokulan, Ravindran Caspa, Horvat, Andela, Yermalitskaya, Liudmila, Korolkova, Olga, Washington, Kay M., El-Rifai, Wael, Dikalov, Sergey I., Zaika, Alexander I.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577233/
https://ncbi.nlm.nih.gov/pubmed/28855537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09620-4
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