Activation of NADPH oxidases leads to DNA damage in esophageal cells

Gastroesophageal reflux disease (GERD) is the strongest known risk factor for esophageal adenocarcinoma. In the center of tumorigenic events caused by GERD is repeated damage of esophageal tissues by the refluxate. In this study, we focused on a genotoxic aspect of exposure of esophageal cells to ac...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Bhardwaj, Vikas, Gokulan, Ravindran Caspa, Horvat, Andela, Yermalitskaya, Liudmila, Korolkova, Olga, Washington, Kay M., El-Rifai, Wael, Dikalov, Sergey I., Zaika, Alexander I.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577233/
https://ncbi.nlm.nih.gov/pubmed/28855537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09620-4
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