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The hexadehydro-Diels-Alder (HDDA) cycloisomerization reaction proceeds by a stepwise mechanism

We report here experiments showing that the hexadehydro-Diels–Alder (HDDA) cycloisomerization reaction proceeds in a stepwise manner—i.e., via a diradical intermediate. Judicious use of substituent effects was decisive. We prepared: (i) a series of triyne HDDA substrates that differed only in the gr...

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Pubblicato in:J Am Chem Soc
Autori principali: Wang, Tao, Niu, Dawen, Hoye, Thomas R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5136458/
https://ncbi.nlm.nih.gov/pubmed/27266843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b03786
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