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A multicomponent approach for the preparation of homoallylic alcohols

Here we report the in situ generation of transient allylic boronic species, by reacting TMSCHN(2) and E-vinyl boronic acids, followed by their subsequent trapping with aldehydes as electrophiles to yield homoallylic alcohols. This metal-free reaction was initially discovered by the use of a flow che...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Poh, Jian-Siang, Lau, Shing-Hing, Dykes, Iain G., Tran, Duc N., Battilocchio, Claudio, Ley, Steven V.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5134730/
https://ncbi.nlm.nih.gov/pubmed/28042466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc02581a
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