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A multistep continuous flow synthesis machine for the preparation of pyrazoles via a metal-free amine-redox process

A versatile multistep continuous flow setup is reported for the four-step conversion of anilines into pyrazole products. The synthesis machine incorporates the use of amine-redox chemistry through diazotization and a metal-free vitamin C mediated reduction. The machine can be used for the synthesis...

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Detalhes bibliográficos
Publicado no:React Chem Eng
Main Authors: Poh, Jian-Siang, Browne, Duncan L., Ley, Steven V.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906367/
https://ncbi.nlm.nih.gov/pubmed/27398231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5re00082c
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