載入...
Rapid Asymmetric Synthesis of Disubstituted Allenes by Coupling of Flow‐Generated Diazo Compounds and Propargylated Amines
We report herein the asymmetric coupling of flow‐generated unstabilized diazo compounds and propargylated amine derivatives, using a new pyridinebis(imidazoline) ligand, a copper catalyst and base. The reaction proceeds rapidly, generating chiral allenes in 10–20 minutes with high enantioselectivity...
Na minha lista:
| 發表在: | Angew Chem Int Ed Engl |
|---|---|
| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
John Wiley and Sons Inc.
2017
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5363227/ https://ncbi.nlm.nih.gov/pubmed/28075518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201611067 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|