Desferrioxamine reduces ultrahigh-molecular-weight polyethylene-induced osteolysis by restraining inflammatory osteoclastogenesis via heme oxygenase-1

As wear particles-induced osteolysis still remains the leading cause of early implant loosening in endoprosthetic surgery, and promotion of osteoclastogenesis by wear particles has been confirmed to be responsible for osteolysis. Therapeutic agents targeting osteoclasts formation are considered for...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Kang, Hui, Yan, Yufei, Jia, Peng, Yang, Kai, Guo, Changjun, Chen, Hao, Qi, Jin, Qian, Niandong, Xu, Xing, Wang, Fei, Li, Changwei, Guo, Lei, Deng, Lianfu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133998/
https://ncbi.nlm.nih.gov/pubmed/27787522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.339
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