Desferrioxamine reduces ultrahigh-molecular-weight polyethylene-induced osteolysis by restraining inflammatory osteoclastogenesis via heme oxygenase-1

As wear particles-induced osteolysis still remains the leading cause of early implant loosening in endoprosthetic surgery, and promotion of osteoclastogenesis by wear particles has been confirmed to be responsible for osteolysis. Therapeutic agents targeting osteoclasts formation are considered for...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Kang, Hui, Yan, Yufei, Jia, Peng, Yang, Kai, Guo, Changjun, Chen, Hao, Qi, Jin, Qian, Niandong, Xu, Xing, Wang, Fei, Li, Changwei, Guo, Lei, Deng, Lianfu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133998/
https://ncbi.nlm.nih.gov/pubmed/27787522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.339
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