A selected small molecule prevents inflammatory osteolysis through restraining osteoclastogenesis by modulating PTEN activity

BACKGROUND: Inflammatory osteolysis is a severe infectious bone disorder that occurs during orthopaedic surgery and is caused by disruptions in the dynamic balance of bone matrix homeostasis, which makes this condition a burden on surgical procedures. Developing novel therapeutic drugs about inhibit...

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Vydáno v:Clin Transl Med
Hlavní autoři: Chen, Yueqi, Hu, Wenhui, Wang, Yiran, Li, Yuheng, Li, Xiaoming, Li, Haibo, Tang, Yong, Zhang, Lincheng, Dong, Yutong, Yang, Xiaochao, Wei, Ye, Dong, Shiwu
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708775/
https://ncbi.nlm.nih.gov/pubmed/33377656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ctm2.240
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