Desferrioxamine reduces ultrahigh-molecular-weight polyethylene-induced osteolysis by restraining inflammatory osteoclastogenesis via heme oxygenase-1

As wear particles-induced osteolysis still remains the leading cause of early implant loosening in endoprosthetic surgery, and promotion of osteoclastogenesis by wear particles has been confirmed to be responsible for osteolysis. Therapeutic agents targeting osteoclasts formation are considered for...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Death Dis
Main Authors: Kang, Hui, Yan, Yufei, Jia, Peng, Yang, Kai, Guo, Changjun, Chen, Hao, Qi, Jin, Qian, Niandong, Xu, Xing, Wang, Fei, Li, Changwei, Guo, Lei, Deng, Lianfu
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133998/
https://ncbi.nlm.nih.gov/pubmed/27787522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.339
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