Loss of Rictor with aging in osteoblasts promotes age-related bone loss

Osteoblast dysfunction is a major cause of age-related bone loss, but the mechanisms underlying changes in osteoblast function with aging are poorly understood. This study demonstrates that osteoblasts in aged mice exhibit markedly impaired adhesion to the bone formation surface and reduced minerali...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Lai, Pinling, Song, Qiancheng, Yang, Cheng, Li, Zhen, Liu, Sichi, Liu, Bin, Li, Mangmang, Deng, Hongwen, Cai, Daozhang, Jin, Dadi, Liu, Anling, Bai, Xiaochun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133960/
https://ncbi.nlm.nih.gov/pubmed/27735936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.249
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