Loss of Rictor with aging in osteoblasts promotes age-related bone loss

Osteoblast dysfunction is a major cause of age-related bone loss, but the mechanisms underlying changes in osteoblast function with aging are poorly understood. This study demonstrates that osteoblasts in aged mice exhibit markedly impaired adhesion to the bone formation surface and reduced minerali...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Dis
Hauptverfasser: Lai, Pinling, Song, Qiancheng, Yang, Cheng, Li, Zhen, Liu, Sichi, Liu, Bin, Li, Mangmang, Deng, Hongwen, Cai, Daozhang, Jin, Dadi, Liu, Anling, Bai, Xiaochun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133960/
https://ncbi.nlm.nih.gov/pubmed/27735936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.249
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