Loss of Rictor with aging in osteoblasts promotes age-related bone loss

Osteoblast dysfunction is a major cause of age-related bone loss, but the mechanisms underlying changes in osteoblast function with aging are poorly understood. This study demonstrates that osteoblasts in aged mice exhibit markedly impaired adhesion to the bone formation surface and reduced minerali...

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Dades bibliogràfiques
Publicat a:Cell Death Dis
Autors principals: Lai, Pinling, Song, Qiancheng, Yang, Cheng, Li, Zhen, Liu, Sichi, Liu, Bin, Li, Mangmang, Deng, Hongwen, Cai, Daozhang, Jin, Dadi, Liu, Anling, Bai, Xiaochun
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133960/
https://ncbi.nlm.nih.gov/pubmed/27735936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.249
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