Osteoblasts secrete Cxcl9 to regulate angiogenesis in bone

Communication between osteoblasts and endothelial cells (ECs) is essential for bone turnover, but the molecular mechanisms of such communication are not well defined. Here we identify Cxcl9 as an angiostatic factor secreted by osteoblasts in the bone marrow microenvironment. We show that Cxcl9 produ...

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Pubblicato in:Nat Commun
Autori principali: Huang, Bin, Wang, Wenhao, Li, Qingchu, Wang, Zhenyu, Yan, Bo, Zhang, Zhongmin, Wang, Liang, Huang, Minjun, Jia, Chunhong, Lu, Jiansen, Liu, Sichi, Chen, Hongdong, Li, Mangmang, Cai, Daozhang, Jiang, Yu, Jin, Dadi, Bai, Xiaochun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5171795/
https://ncbi.nlm.nih.gov/pubmed/27966526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13885
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