Increased Osteoblastic Cxcl9 Contributes to the Uncoupled Bone Formation and Resorption in Postmenopausal Osteoporosis

INTRODUCTION: Estrogen deficiency leads to bone loss in postmenopausal osteoporosis, because bone formation, albeit enhanced, fails to keep pace with the stimulated osteoclastic bone resorption. The mechanism driving this uncoupling is central to the pathogenesis of postmenopausal osteoporosis, whic...

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Détails bibliographiques
Publié dans:Clin Interv Aging
Auteurs principaux: Liu, Zezheng, Liang, Wenquan, Kang, Dawei, Chen, Qingjing, Ouyang, Zhicong, Yan, Huibo, Huang, Bin, Jin, Dadi, Chen, Yinkui, Li, Qingchu
Format: Artigo
Langue:Inglês
Publié: Dove 2020
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7381095/
https://ncbi.nlm.nih.gov/pubmed/32764906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CIA.S254885
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