Increased Osteoblastic Cxcl9 Contributes to the Uncoupled Bone Formation and Resorption in Postmenopausal Osteoporosis

INTRODUCTION: Estrogen deficiency leads to bone loss in postmenopausal osteoporosis, because bone formation, albeit enhanced, fails to keep pace with the stimulated osteoclastic bone resorption. The mechanism driving this uncoupling is central to the pathogenesis of postmenopausal osteoporosis, whic...

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Bibliografiske detaljer
Udgivet i:Clin Interv Aging
Main Authors: Liu, Zezheng, Liang, Wenquan, Kang, Dawei, Chen, Qingjing, Ouyang, Zhicong, Yan, Huibo, Huang, Bin, Jin, Dadi, Chen, Yinkui, Li, Qingchu
Format: Artigo
Sprog:Inglês
Udgivet: Dove 2020
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7381095/
https://ncbi.nlm.nih.gov/pubmed/32764906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CIA.S254885
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