Orcinol glucoside facilitates the shift of MSC fate to osteoblast and prevents adipogenesis via Wnt/β-catenin signaling pathway

BACKGROUND: During osteoporosis, bone mesenchymal stem cells (BMSCs) lineage commitment shifts to adipocytes, causing fat accumulation and bone loss in the skeleton. Seeking drugs that could reverse the adipocyte fate determination of BMSCs is critical for osteoporosis therapy. As a traditional Chin...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Drug Des Devel Ther
Egile Nagusiak: Zhou, Xinying, Liu, Zezheng, Huang, Bin, Yan, Huibo, Yang, Changsheng, Li, Qingchu, Jin, Dadi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Dove 2019
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689118/
https://ncbi.nlm.nih.gov/pubmed/31496649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S208458
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