Increased Osteoblastic Cxcl9 Contributes to the Uncoupled Bone Formation and Resorption in Postmenopausal Osteoporosis

INTRODUCTION: Estrogen deficiency leads to bone loss in postmenopausal osteoporosis, because bone formation, albeit enhanced, fails to keep pace with the stimulated osteoclastic bone resorption. The mechanism driving this uncoupling is central to the pathogenesis of postmenopausal osteoporosis, whic...

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Detalhes bibliográficos
Publicado no:Clin Interv Aging
Main Authors: Liu, Zezheng, Liang, Wenquan, Kang, Dawei, Chen, Qingjing, Ouyang, Zhicong, Yan, Huibo, Huang, Bin, Jin, Dadi, Chen, Yinkui, Li, Qingchu
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7381095/
https://ncbi.nlm.nih.gov/pubmed/32764906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CIA.S254885
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