Loss of Rictor with aging in osteoblasts promotes age-related bone loss

Osteoblast dysfunction is a major cause of age-related bone loss, but the mechanisms underlying changes in osteoblast function with aging are poorly understood. This study demonstrates that osteoblasts in aged mice exhibit markedly impaired adhesion to the bone formation surface and reduced minerali...

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Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Lai, Pinling, Song, Qiancheng, Yang, Cheng, Li, Zhen, Liu, Sichi, Liu, Bin, Li, Mangmang, Deng, Hongwen, Cai, Daozhang, Jin, Dadi, Liu, Anling, Bai, Xiaochun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133960/
https://ncbi.nlm.nih.gov/pubmed/27735936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.249
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