Structural and Functional Elucidation of Yeast Lanosterol 14α-Demethylase in Complex with Agrochemical Antifungals

Azole antifungals, known as demethylase inhibitors (DMIs), target sterol 14α-demethylase (CYP51) in the ergosterol biosynthetic pathway of fungal pathogens of both plants and humans. DMIs remain the treatment of choice in crop protection against a wide range of fungal phytopathogens that have the po...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Tyndall, Joel D. A., Sabherwal, Manya, Sagatova, Alia A., Keniya, Mikhail V., Negroni, Jacopo, Wilson, Rajni K., Woods, Matthew A., Tietjen, Klaus, Monk, Brian C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5132298/
https://ncbi.nlm.nih.gov/pubmed/27907120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167485
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky